Pericellular Versican Regulates the Fibroblast-Myofibroblast Transition: A ROLE FOR ADAMTS5 PROTEASE-MEDIATED PROTEOLYSIS

The cell and its glycosaminoglycan-rich pericellular matrix (PCM) comprise a functional unit. Because modification of PCM influences cell behavior, we investigated molecular mechanisms that regulate PCM volume and composition. In fibroblasts and other cells, aggregates of hyaluronan and versican are...

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Bibliografiske detaljer
Main Authors: Hattori, Noriko, Carrino, David A., Lauer, Mark E., Vasanji, Amit, Wylie, James D., Nelson, Courtney M., Apte, Suneel S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190794/
https://ncbi.nlm.nih.gov/pubmed/21828051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254938
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