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Versican Proteolysis by ADAMTS Proteases and Its Influence on Sex Steroid Receptor Expression in Uterine Leiomyoma
CONTEXT: Leiomyomas have abundant extracellular matrix (ECM), with upregulation of versican, a large proteoglycan. OBJECTIVE: We investigated ADAMTS (a disintegrin-like and metalloprotease with thrombospondin type 1 motifs) protease-mediated versican cleavage in myometrium and leiomyoma and the effe...
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| Publié dans: | J Clin Endocrinol Metab |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Endocrine Society
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5443325/ https://ncbi.nlm.nih.gov/pubmed/28323982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-3527 |
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