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A Combination of Multisite Phosphorylation and Substrate Sequestration Produces Switchlike Responses

The phosphorylation of a protein on multiple sites has been proposed to promote the switchlike regulation of protein activity. Recent theoretical work, however, indicates that multisite phosphorylation, by itself, is less effective at creating switchlike responses than had been previously thought. T...

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Bibliografische gegevens
Hoofdauteurs: Liu, Xinfeng, Bardwell, Lee, Nie, Qing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856190/
https://ncbi.nlm.nih.gov/pubmed/20409458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.12.4307
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