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Formation of Intracellular Concentration Landscapes by Multisite Protein Modification

Multiple cellular proteins are covalently modified (e.g., phosphorylated/dephosphorylated) at several sites, which leads to diverse signaling activities. Here, we consider a signaling cascade that is activated at the plasma membrane and composed of two-site protein modification cycles, and we focus...

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Detalhes bibliográficos
Main Authors: Muñoz-García, Javier, Kholodenko, Boris N., Neufeld, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895390/
https://ncbi.nlm.nih.gov/pubmed/20655833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.014
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