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A Combination of Multisite Phosphorylation and Substrate Sequestration Produces Switchlike Responses

The phosphorylation of a protein on multiple sites has been proposed to promote the switchlike regulation of protein activity. Recent theoretical work, however, indicates that multisite phosphorylation, by itself, is less effective at creating switchlike responses than had been previously thought. T...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Liu, Xinfeng, Bardwell, Lee, Nie, Qing
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Biophysical Society 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856190/
https://ncbi.nlm.nih.gov/pubmed/20409458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.12.4307
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