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Substrate-Dependent Control of ERK Phosphorylation Can Lead to Oscillations
The extracellular signal-regulated kinase (ERK) controls cellular processes by phosphorylating multiple substrates. The ERK protein can use the same domains to interact with phosphatases, which dephosphorylate and deactivate ERK, and with substrates, which connect ERK to its downstream effects. As a...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3297790/ https://ncbi.nlm.nih.gov/pubmed/22261044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.10.025 |
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