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Hexameric Helicase Deconstructed: Interplay of Conformational Changes and Substrate Coupling
Hexameric helicases are molecular motor proteins that utilize energy obtained from ATP hydrolysis to translocate along and/or unwind nucleic acids. In this study, we investigate the dynamic behavior of the Simian Virus 40 hexameric helicase bound to DNA by performing molecular dynamics simulations e...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856183/ https://ncbi.nlm.nih.gov/pubmed/20409463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.12.4315 |
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