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Deconstructing activation events in rhodopsin
Activation of class A G-protein coupled receptors (GPCRs) involves large-scale reorganization of the H3/H6 interhelical network. In rhodopsin (Rh), this process is coupled to a change in the protonation state of a key residue, E134, whose exact role in activation is not well understood. Capturing th...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774788/ https://ncbi.nlm.nih.gov/pubmed/23841875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4042687 |
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