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Large-scale allosteric conformational transitions of adenylate kinase appear to involve a population-shift mechanism
Large-scale conformational changes in proteins are often associated with the binding of a substrate. Because conformational changes may be related to the function of an enzyme, understanding the kinetics and energetics of these motions is very important. We have delineated the atomically detailed co...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2141805/ https://ncbi.nlm.nih.gov/pubmed/18000050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706443104 |
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