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Conformational transitions of Adenylate Kinase: switching by cracking

Conformational heterogeneity in proteins is known to often be the key to their function. We present a coarse grained model to explore the interplay between protein structure, folding and function which is applicable to allosteric or non-allosteric proteins. We employ the model to study the detailed...

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Detalhes bibliográficos
Main Authors: Whitford, Paul C., Miyashita, Osamu, Levy, Yaakov, Onuchic, José N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561047/
https://ncbi.nlm.nih.gov/pubmed/17217965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.085
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