Model-based prediction of defective DNA mismatch repair using clinicopathological variables in sporadic colon cancer patients

BACKGROUND: Colon cancers with defective DNA mismatch repair (MMR) have a favorable prognosis and may lack benefit from 5-fluorouracil-based adjuvant chemotherapy. We developed models to predict MMR deficiency in sporadic colon cancer patients using routine clinical and pathological data. METHODS: T...

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Main Authors: Sinicrope, Frank, Foster, N.R., Sargent, D.J., Thibodeau, S.N., Smyrk, T.C., O'Connell, M.J.
格式: Artigo
語言:Inglês
出版: 2010
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855300/
https://ncbi.nlm.nih.gov/pubmed/20186699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24913
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