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DNA mismatch repair and adjuvant chemotherapy in sporadic colon cancer
Defective DNA mismatch repair (MMR) occurs in approximately 15% of sporadic colorectal cancers (CRCs). Multiple retrospective studies have shown that patients with MMR-deficient CRCs have a more favorable stage-adjusted prognosis compared with those who have MMR-proficient tumors. Evidence also indi...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767984/ https://ncbi.nlm.nih.gov/pubmed/20190798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2009.235 |
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