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DNA mismatch repair and adjuvant chemotherapy in sporadic colon cancer

Defective DNA mismatch repair (MMR) occurs in approximately 15% of sporadic colorectal cancers (CRCs). Multiple retrospective studies have shown that patients with MMR-deficient CRCs have a more favorable stage-adjusted prognosis compared with those who have MMR-proficient tumors. Evidence also indi...

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Autor principal: Sinicrope, Frank A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767984/
https://ncbi.nlm.nih.gov/pubmed/20190798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2009.235
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