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Prognostic Significance of Defective Mismatch Repair and BRAF-V600E in Patients with Colon Cancer

PURPOSE: Colon tumors with defective DNA mismatch repair (dMMR) have a well characterized phenotype and accounts for ~15–20% of sporadic colon cancer (CC) as well as those colon cancer patients with Lynch Syndrome. Although the presence of dMMR appears to be a favorable prognostic marker, data sugge...

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Detalhes bibliográficos
Main Authors: French, Amy J., Sargent, Daniel J., Burgart, Lawrence J., Foster, Nathan R., Kabat, Brian F., Goldberg, Richard, Shepherd, Lois, Windschitl, Harold E., Thibodeau, Stephen N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674786/
https://ncbi.nlm.nih.gov/pubmed/18519771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-1489
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