Proapoptotic Bad and Bid Protein Expression Predict Survival in Stages II and III Colon Cancers

PURPOSE: Proapoptotic BH3-only proteins Bad and Bid initiate apoptosis by binding to regulatory sites on prosurvival Bcl-2 proteins to directly neutralize their function. We determined if expression of these proteins in colon cancers may account for differences in patient survival. EXPERIMENTAL DESI...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Sinicrope, Frank A., Rego, Rafaela L., Foster, Nathan R., Thibodeau, Stephen N., Alberts, Steven R., Windschitl, Harold E., Sargent, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948489/
https://ncbi.nlm.nih.gov/pubmed/18593990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-5160
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker