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Neurofibromin-deficient fibroblasts fail to form perineurium in vitro

To identify cell type(s) that might contribute to nerve sheath tumors (neurofibromas) in patients with neurofibromatosis type 1, we generated cell cultures containing neurons, Schwann cells and fibroblasts from transgenic mouse embryos in which the type 1 neurofibromatosis gene was disrupted by homo...

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Detalhes bibliográficos
Main Authors: Rosenbaum, Thorsten, Boissy, Ying L., Kombrinck, Keith, Brannan, Camilynn I., Jenkins, Nancy A., Copeland, Neal G., Ratner, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854496/
https://ncbi.nlm.nih.gov/pubmed/8582272
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