Detection of Amino-terminal Extracellular Domain of Somatostatin Receptor 2 by Specific Monoclonal Antibodies and Quantification of Receptor Density in Medulloblastoma

Somatostatin receptor 2 (SSTR2) is expressed by most medulloblastomas (MEDs). We isolated monoclonal antibodies (MAbs) to the 12-mer (33)QTEPYYDLTSNA(44), which resides in the extracellular domain of the SSTR2 amino terminus, screened the peptide-bound MAbs by fluorescence microassay on D341 and D28...

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Detalhes bibliográficos
Main Authors: Kuan, Chien-Tsun, Wikstrand, Carol J., McLendon, Roger E., Zalutsky, Michael R., Kumar, Ujendra, Bigner, Darell D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854495/
https://ncbi.nlm.nih.gov/pubmed/20025498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hyb.2009.0049
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