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Recombinant single-chain variable fragment antibodies against extracellular epitopes of human multidrug resistance protein MRP3 for targeting malignant gliomas
MRP3, a multidrug resistance protein identified by serial analysis of gene expression as a glioblastoma multiforme (GBM)-associated molecule, is highly expressed in GBM, but not in normal brain cells. Thus MRP3 is a candidate for GBM immunotargeting, but to date, no monoclonal antibody has been isol...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878888/ https://ncbi.nlm.nih.gov/pubmed/19937796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25062 |
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