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A Monoclonal Antibody IMab-1 Specifically Recognizes IDH1(R132H), the Most Common Glioma-Derived Mutation
IDH1 (isocitrate dehydrogenase 1) mutations have been identified as early and frequent genetic alterations in astrocytomas, oligodendrogliomas, and oligoastrocytomas as well as secondary glioblastomas. In contrast, primary glioblastomas very rarely contain IDH1 mutations, although primary and second...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788025/ https://ncbi.nlm.nih.gov/pubmed/19818334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.10.001 |
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