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Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome
Trisomy of human chromosome 21 (Hsa21) results in Down syndrome (DS), a disorder that affects many aspects of physiology, including hematopoiesis. DS children have greatly increased rates of acute lymphoblastic leukemia and acute megakaryoblastic leukemia (AMKL); DS newborns present with transient m...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854435/ https://ncbi.nlm.nih.gov/pubmed/20154221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-227629 |
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