Perturbation of fetal hematopoiesis in a mouse model of Down syndrome’s transient myeloproliferative disorder

Children with Down syndrome develop a unique congenital clonal megakaryocytic proliferation disorder (transient myeloproliferative disorder [TMD]). It is caused by an expansion of fetal megakaryocyte-erythroid progenitors (MEPs) triggered by trisomy of chromosome 21 and is further enhanced by the so...

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Bibliografski detalji
Glavni autori: Birger, Yehudit, Goldberg, Liat, Chlon, Timothy M., Goldenson, Benjamin, Muler, Inna, Schiby, Ginette, Jacob-Hirsch, Jasmin, Rechavi, Gideon, Crispino, John D., Izraeli, Shai
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2013
Teme:
Myeloid Neoplasia
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739041/
https://ncbi.nlm.nih.gov/pubmed/23719302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-460998
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