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DYRK1A in Down syndrome: an oncogene or tumor suppressor?
Children with Down syndrome (DS) have a markedly increased risk of developing acute megakaryoblastic leukemia (AMKL) and acute lymphoblastic leukemia compared with that of children without DS. Despite recent breakthroughs, it is not clear which genes on chromosome 21, the chromosome that is trisomic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287238/ https://ncbi.nlm.nih.gov/pubmed/22354166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62372 |
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