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Rap1 and its regulatory proteins: The tumor suppressor, oncogene, tumor suppressor gene axis in head and neck cancer

Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer, globally. Previously, we showed that Rap1GAP is a tumor suppressor gene that inhibits tumor growth, but promotes invasion in SCCHN. In this work, we discuss the role of Rap1 and Rap1GAP in SCCHN progression in the...

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Detalles Bibliográficos
Main Authors: Banerjee, Rajat, Russo, Nickole, Liu, Min, Van Tubergen, Elizabeth, D'Silva, Nisha J.
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442808/
https://ncbi.nlm.nih.gov/pubmed/22684501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.20413
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