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Rap1 and its regulatory proteins: The tumor suppressor, oncogene, tumor suppressor gene axis in head and neck cancer

Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer, globally. Previously, we showed that Rap1GAP is a tumor suppressor gene that inhibits tumor growth, but promotes invasion in SCCHN. In this work, we discuss the role of Rap1 and Rap1GAP in SCCHN progression in the...

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Bibliographische Detailangaben
Hauptverfasser: Banerjee, Rajat, Russo, Nickole, Liu, Min, Van Tubergen, Elizabeth, D'Silva, Nisha J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442808/
https://ncbi.nlm.nih.gov/pubmed/22684501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.20413
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