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Rap1 mediates Galanin receptor 2-induced proliferation and survival in squamous cell carcinoma

Previously we showed that galanin, a neuropeptide, is secreted by human squamous cell carcinoma of the head and neck (SCCHN) in which it exhibits an autocrine mitogenic effect. We also showed that rap1, a ras-like signaling protein, is a critical mediator of SCCHN progression. Given the emerging imp...

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Detalhes bibliográficos
Main Authors: Banerjee, Rajat, Henson, Bradley S, Russo, Nickole, Tsodikov, Alex, D’Silva, Nisha J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090707/
https://ncbi.nlm.nih.gov/pubmed/21345369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.02.002
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