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MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome
Children with Down syndrome (DS) are at increased risk for acute myeloid leukemias (ML-DS) characterized by mixed megakaryocytic and erythroid phenotype and by acquired mutations in the GATA1 gene resulting in a short GATA1s isoform. The chromosome 21 microRNA (miR)-125b cluster has been previously...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335082/ https://ncbi.nlm.nih.gov/pubmed/25533034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-581892 |
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