MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome

Children with Down syndrome (DS) are at increased risk for acute myeloid leukemias (ML-DS) characterized by mixed megakaryocytic and erythroid phenotype and by acquired mutations in the GATA1 gene resulting in a short GATA1s isoform. The chromosome 21 microRNA (miR)-125b cluster has been previously...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Shaham, Lital, Vendramini, Elena, Ge, Yubin, Goren, Yaron, Birger, Yehudit, Tijssen, Marloes R., McNulty, Maureen, Geron, Ifat, Schwartzman, Omer, Goldberg, Liat, Chou, Stella T., Pitman, Holly, Weiss, Mitchell J., Michaeli, Shulamit, Sredni, Benjamin, Göttgens, Berthold, Crispino, John D., Taub, Jeffrey W., Izraeli, Shai
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335082/
https://ncbi.nlm.nih.gov/pubmed/25533034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-581892
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