MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome

Children with Down syndrome (DS) are at increased risk for acute myeloid leukemias (ML-DS) characterized by mixed megakaryocytic and erythroid phenotype and by acquired mutations in the GATA1 gene resulting in a short GATA1s isoform. The chromosome 21 microRNA (miR)-125b cluster has been previously...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Shaham, Lital, Vendramini, Elena, Ge, Yubin, Goren, Yaron, Birger, Yehudit, Tijssen, Marloes R., McNulty, Maureen, Geron, Ifat, Schwartzman, Omer, Goldberg, Liat, Chou, Stella T., Pitman, Holly, Weiss, Mitchell J., Michaeli, Shulamit, Sredni, Benjamin, Göttgens, Berthold, Crispino, John D., Taub, Jeffrey W., Izraeli, Shai
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335082/
https://ncbi.nlm.nih.gov/pubmed/25533034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-581892
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