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OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer

MicroRNAs are short, noncoding RNAs whose dysregulation has been implicated in most, if not all, cancers. They regulate gene expression by suppressing mRNA translation and reducing mRNA stability. To this end, there is a great deal of interest in modifying miRNA expression levels for the treatment o...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Svoronos, Alexander A., Engelman, Donald M., Slack, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930690/
https://ncbi.nlm.nih.gov/pubmed/27325641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0359
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