Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome

Down syndrome (DS) is a genetic disorder arising from the presence of a third copy of human chromosome 21 (Hsa21). Recently, O'Doherty et al. [An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. Science 309 (2005) 2033–2037] generated a trans-species aneuploid...

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Main Authors: Galante, Micaela, Jani, Harsha, Vanes, Lesley, Daniel, Hervé, Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Bliss, Timothy V.P., Morice, Elise
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664148/
https://ncbi.nlm.nih.gov/pubmed/19181682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp055
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