Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome

Down syndrome (DS) is a genetic disorder arising from the presence of a third copy of the human chromosome 21 (Hsa21). Recently, O’Doherty and colleagues in an earlier study generated a new genetic mouse model of DS (Tc1) that carries an almost complete Hsa21. Since DS is the most common genetic cau...

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Detalhes bibliográficos
Main Authors: Morice, Elise, Andreae, Laura C., Cooke, Sam F., Vanes, Lesley, Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Bliss, Timothy V.P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2505316/
https://ncbi.nlm.nih.gov/pubmed/18626093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.969608
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