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Design, Synthesis and Biological Evaluation of EF- and ABEF-Analogs of (+)-Spongistatin 1
[Image: see text] The design, synthesis and biological evaluation of two potential (+)-spongistatin 1 analogs have been achieved. The analogs, incorporating tethers (red) in place of the ABCD and the CD components of the (+)-spongistatin 1 macrolide were designed such that the conformations of the r...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853872/ https://ncbi.nlm.nih.gov/pubmed/20297810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100418n |
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