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Design, Synthesis and Biological Evaluation of EF- and ABEF-Analogs of (+)-Spongistatin 1

[Image: see text] The design, synthesis and biological evaluation of two potential (+)-spongistatin 1 analogs have been achieved. The analogs, incorporating tethers (red) in place of the ABCD and the CD components of the (+)-spongistatin 1 macrolide were designed such that the conformations of the r...

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Hlavní autoři: Smith, Amos B., Risatti, Christina A., Atasoylu, Onur, Bennett, Clay S., TenDyke, Karen, Xu, Qunli
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853872/
https://ncbi.nlm.nih.gov/pubmed/20297810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100418n
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