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DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF DIMUNITIVE FORMS OF (+)- SPONGISTATIN 1: LESSONS LEARNED

[Image: see text] The design, synthesis, and biological evaluation of two diminutive forms of (+)-spongistatin 1, in conjunction with the development of a potentially general design strategy to simplify highly flexible macrocyclic molecules while maintaining biological activity, have been achieved....

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Main Authors: Smith, Amos B., Risatti, Christina A., Atasoylu, Onur, Bennett, Clay S., Liu, Junke, Cheng, Hongsheng, TenDyke, Karen, Xu, Qunli
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164888/
https://ncbi.nlm.nih.gov/pubmed/21761891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2046167
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