Uncoupled responses of Smad4-deficient cancer cells to TNFα result in secretion of monomeric laminin-γ2

BACKGROUND: Functional loss of the tumor suppressor Smad4 is involved in pancreatic and colorectal carcinogenesis and has been associated with the acquisition of invasiveness. We have previously demonstrated that the heterotrimeric basement membrane protein laminin-332 is a Smad4 target. Namely, Sma...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zboralski, Dirk, Warscheid, Bettina, Klein-Scory, Susanne, Malas, M Bassel, Becker, Heiko, Böckmann, Miriam, Meyer, Helmut E, Schmiegel, Wolff, Simon-Assmann, Patricia, Schwarte-Waldhoff, Irmgard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853515/
https://ncbi.nlm.nih.gov/pubmed/20307265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-65
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