Isoketals form cytotoxic phosphatidylethanolamine adducts in cells

Levuglandins and their stereo- and regio-isomers (termed isolevuglandins or isoketals) are γ-ketoaldehydes (IsoK) that rapidly react with lysines to form stable protein adducts. IsoK protein adduct levels increase in several pathological conditions including cardiovascular disease. IsoKs can induce...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Sullivan, C. Blake, Matafonova, Elena, Roberts, L. Jackson, Amarnath, Venkataraman, Davies, Sean S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853468/
https://ncbi.nlm.nih.gov/pubmed/19965577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M001040
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi