DC isoketal-modified proteins activate T cells and promote hypertension

Oxidative damage and inflammation are both implicated in the genesis of hypertension; however, the mechanisms by which these stimuli promote hypertension are not fully understood. Here, we have described a pathway in which hypertensive stimuli promote dendritic cell (DC) activation of T cells, ultim...

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Publicado en:J Clin Invest
Main Authors: Kirabo, Annet, Fontana, Vanessa, de Faria, Ana P.C., Loperena, Roxana, Galindo, Cristi L., Wu, Jing, Bikineyeva, Alfiya T., Dikalov, Sergey, Xiao, Liang, Chen, Wei, Saleh, Mohamed A., Trott, Daniel W., Itani, Hana A., Vinh, Antony, Amarnath, Venkataraman, Amarnath, Kalyani, Guzik, Tomasz J., Bernstein, Kenneth E., Shen, Xiao Z., Shyr, Yu, Chen, Sheau-chiann, Mernaugh, Raymond L., Laffer, Cheryl L., Elijovich, Fernando, Davies, Sean S., Moreno, Heitor, Madhur, Meena S., Roberts, Jackson, Harrison, David G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220659/
https://ncbi.nlm.nih.gov/pubmed/25244096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74084
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