DC isoketal-modified proteins activate T cells and promote hypertension

Oxidative damage and inflammation are both implicated in the genesis of hypertension; however, the mechanisms by which these stimuli promote hypertension are not fully understood. Here, we have described a pathway in which hypertensive stimuli promote dendritic cell (DC) activation of T cells, ultim...

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Publicat a:J Clin Invest
Autors principals: Kirabo, Annet, Fontana, Vanessa, de Faria, Ana P.C., Loperena, Roxana, Galindo, Cristi L., Wu, Jing, Bikineyeva, Alfiya T., Dikalov, Sergey, Xiao, Liang, Chen, Wei, Saleh, Mohamed A., Trott, Daniel W., Itani, Hana A., Vinh, Antony, Amarnath, Venkataraman, Amarnath, Kalyani, Guzik, Tomasz J., Bernstein, Kenneth E., Shen, Xiao Z., Shyr, Yu, Chen, Sheau-chiann, Mernaugh, Raymond L., Laffer, Cheryl L., Elijovich, Fernando, Davies, Sean S., Moreno, Heitor, Madhur, Meena S., Roberts, Jackson, Harrison, David G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220659/
https://ncbi.nlm.nih.gov/pubmed/25244096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74084
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