DC isoketal-modified proteins activate T cells and promote hypertension

Oxidative damage and inflammation are both implicated in the genesis of hypertension; however, the mechanisms by which these stimuli promote hypertension are not fully understood. Here, we have described a pathway in which hypertensive stimuli promote dendritic cell (DC) activation of T cells, ultim...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kirabo, Annet, Fontana, Vanessa, de Faria, Ana P.C., Loperena, Roxana, Galindo, Cristi L., Wu, Jing, Bikineyeva, Alfiya T., Dikalov, Sergey, Xiao, Liang, Chen, Wei, Saleh, Mohamed A., Trott, Daniel W., Itani, Hana A., Vinh, Antony, Amarnath, Venkataraman, Amarnath, Kalyani, Guzik, Tomasz J., Bernstein, Kenneth E., Shen, Xiao Z., Shyr, Yu, Chen, Sheau-chiann, Mernaugh, Raymond L., Laffer, Cheryl L., Elijovich, Fernando, Davies, Sean S., Moreno, Heitor, Madhur, Meena S., Roberts, Jackson, Harrison, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220659/
https://ncbi.nlm.nih.gov/pubmed/25244096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74084
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