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Isoketals form cytotoxic phosphatidylethanolamine adducts in cells
Levuglandins and their stereo- and regio-isomers (termed isolevuglandins or isoketals) are γ-ketoaldehydes (IsoK) that rapidly react with lysines to form stable protein adducts. IsoK protein adduct levels increase in several pathological conditions including cardiovascular disease. IsoKs can induce...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853468/ https://ncbi.nlm.nih.gov/pubmed/19965577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M001040 |
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