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PKC-α mediates flow-stimulated superoxide production in thick ascending limbs
We showed that luminal flow increases net superoxide (O(2)(−)) production via NADPH oxidase in thick ascending limbs. Protein kinase C (PKC) activates NADPH oxidase activity in phagocytes, cardiomyocytes, aortic endothelial cells, vascular smooth muscle cells, and renal mesangial cells. However, the...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853312/ https://ncbi.nlm.nih.gov/pubmed/20053794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00543.2009 |
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