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Angiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4
Angiotensin II (ANG II) stimulates production of superoxide (O(2)(−)) by NADPH oxidase (NOX) in medullary thick ascending limbs (TALs). There are three isoforms of the catalytic subunit (NOX1, 2, and 4) known to be expressed in the kidney. We hypothesized that NOX2 mediates ANG II-induced O(2)(−) pr...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3469600/ https://ncbi.nlm.nih.gov/pubmed/22875785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00457.2011 |
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