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NADPH oxidase 4 mediates flow-induced superoxide production in thick ascending limbs

We previously showed that luminal flow stimulates thick ascending limb (TAL) superoxide (O(2)(−)) production by stretching epithelial cells and increasing NaCl transport, and reported that the major source of flow-induced O(2)(−) is NADPH oxidase (Nox). However, the specific Nox isoform involved is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hong, Nancy J., Garvin, Jeffrey L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469675/
https://ncbi.nlm.nih.gov/pubmed/22896039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00181.2012
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