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Luminal flow induces NADPH oxidase 4 translocation to the nuclei of thick ascending limbs

Superoxide (O(2) (−)) exerts its physiological actions in part by causing changes in gene transcription. In thick ascending limbs flow‐induced O(2) (−) production is mediated by NADPH oxidase 4 (Nox4) and is dependent on protein kinase C (PKC). Polymerase delta interacting protein 2 (Poldip2) increa...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Saez, Fara, Hong, Nancy J., Garvin, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814881/
https://ncbi.nlm.nih.gov/pubmed/27033446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12724
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