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Endogenous flow-induced superoxide stimulates Na/H exchange activity via PKC in thick ascending limbs
Luminal flow stimulates Na reabsorption along the nephron and activates protein kinase C (PKC) which enhances endogenous superoxide (O(2)(−)) production by thick ascending limbs (TALs). Exogenously-added O(2)(−) augments TAL Na reabsorption, a process also dependent on PKC. Luminal Na/H exchange (NH...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187046/ https://ncbi.nlm.nih.gov/pubmed/25080525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00260.2014 |
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