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Nitric oxide reduces flow-induced superoxide production via cGMP-dependent protein kinase in thick ascending limbs

We have shown that increased luminal flow induces O(2)(−) and nitric oxide (NO) production in thick ascending limbs (TALs). However, the interaction of flow-stimulated NO and O(2)(−) in TALs is unclear. We hypothesized that NO inhibits flow-induced O(2)(−) production in TALs via cGMP-dependent prote...

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Bibliografiska uppgifter
Huvudupphovsmän: Hong, Nancy J., Garvin, Jeffrey L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681368/
https://ncbi.nlm.nih.gov/pubmed/19244401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90707.2008
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