טוען...

Utilization of the 1, 2, 3, 5-Thiatriazolidin-3-one 1, 1-Dioxide Scaffold in the Design of Potential Inhibitors of Human Neutrophil Proteinase 3

The S’ subsites of human neutrophil proteinase 3 (Pr 3) were probed by constructing diverse libraries of compounds based on the 1, 2, 3, 5-thiatriazolidin-3-one 1, 1-dioxide using combinational and click chemistry methods. The multiple points of diversity embodied in the heterocyclic scaffold render...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Dou, Dengfeng, He, Guijia, Li, Yi, Lai, Zhong, Wei, Liuqing, Alliston, Kevin R., Lushington, Gerald H., Eichhorn, David M., Groutas, William C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853038/
https://ncbi.nlm.nih.gov/pubmed/20061159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.12.057
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