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Identification of a Linear Epitope in Sortilin That Partakes in Pro-neurotrophin Binding
Sortilin acts as a cell surface receptor for pro-neurotrophins (pro-NT) that upon complex formation with the p75 neurotrophin receptor (p75(NTR)) is able to signal neuronal cell death. Here we screened a sortilin peptide library comprising 16-mer overlapping sequences for binding of the pro-domains...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852960/ https://ncbi.nlm.nih.gov/pubmed/20159974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.062364 |
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