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Bridging the gap between cytotoxic and biologic therapy with metronomic topotecan and pazopanib in ovarian cancer
To investigate the anti-tumor and anti-angiogenic effects utilizing a novel therapy regimen of metronomic topotecan and pazopanib, a multi-receptor tyrosine kinase inhibitor. In vitro (Western blot) and in vivo dose-finding experiments were performed following pazopanib therapy in ovarian cancer mod...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852465/ https://ncbi.nlm.nih.gov/pubmed/20371710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0967 |
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