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Potent Preclinical Impact of Metronomic Low-Dose Oral Topotecan Combined with the Antiangiogenic Drug Pazopanib for the Treatment of Ovarian Cancer

Low dose metronomic (LDM) chemotherapy has shown promising activity in many preclinical and some phase II clinical trials involving various tumor types. To evaluate the potential therapeutic impact of LDM chemotherapy for ovarian cancer, we developed a preclinical model of advanced disease and teste...

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Detalhes bibliográficos
Main Authors: Hashimoto, Kae, Man, Shan, Xu, Ping, Cruz-Munoz, William, Tang, Terence, Kumar, Rakesh, Kerbel, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852477/
https://ncbi.nlm.nih.gov/pubmed/20371722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0960
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