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Analysis of acquired resistance to metronomic oral topotecan chemotherapy plus pazopanib after prolonged preclinical potent responsiveness in advanced ovarian cancer

An alternative or follow-up adjunct to conventional maximum tolerated dose (MTD) chemotherapy now in advanced phase III clinical trial assessment is metronomic chemotherapy—the close regular administration of low doses of drug with no prolonged breaks. A number of preclinical studies have shown metr...

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Bibliographic Details
Published in:Angiogenesis
Main Authors: Cruz-Muñoz, William, Desidero, Teresa Di, Man, Shan, Xu, Ping, Jaramillo, Maria Luz, Hashimoto, Kae, Collins, Catherine, Banville, Myriam, O’Connor-McCourt, Maureen D, Kerbel, Robert S.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540351/
https://ncbi.nlm.nih.gov/pubmed/24569856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-014-9422-9
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