Targeted deletion of βIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes

The spectrin membrane skeleton controls the disposition of selected membrane channels, receptors, and transporters. In the brain βIII spectrin binds directly to the excitatory amino acid transporter (EAAT4), the glutamate receptor delta, and other proteins. Mutations in βIII spectrin link strongly t...

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Hlavní autoři: Stankewich, Michael C., Gwynn, Babette, Ardito, Thomas, Ji, Lan, Kim, Jung, Robledo, Raymond F., Lux, Samuel E., Peters, Luanne L., Morrow, Jon S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851889/
https://ncbi.nlm.nih.gov/pubmed/20231455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001522107
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