Targeted deletion of βIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes

The spectrin membrane skeleton controls the disposition of selected membrane channels, receptors, and transporters. In the brain βIII spectrin binds directly to the excitatory amino acid transporter (EAAT4), the glutamate receptor delta, and other proteins. Mutations in βIII spectrin link strongly t...

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Bibliografische gegevens
Hoofdauteurs: Stankewich, Michael C., Gwynn, Babette, Ardito, Thomas, Ji, Lan, Kim, Jung, Robledo, Raymond F., Lux, Samuel E., Peters, Luanne L., Morrow, Jon S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2010
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851889/
https://ncbi.nlm.nih.gov/pubmed/20231455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001522107
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