Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

Residues within processed protein fragments bound to major histocompatibility complex class I (MHC-I) glycoproteins have been considered to function as a series of “independent pegs” that either anchor the peptide (p) to the MHC-I and/or interact with the spectrum of αβ-T-cell receptors (TCRs) speci...

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Auteurs principaux: Theodossis, Alex, Guillonneau, Carole, Welland, Andrew, Ely, Lauren K., Clements, Craig S., Williamson, Nicholas A., Webb, Andrew I., Wilce, Jacqueline A., Mulder, Roger J., Dunstone, Michelle A., Doherty, Peter C., McCluskey, James, Purcell, Anthony W., Turner, Stephen J., Rossjohn, Jamie
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851776/
https://ncbi.nlm.nih.gov/pubmed/20212169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000032107
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